Table 4. Univariable analysis of time to TB episode; hazard ratios, 95% CI and P-values (nmax = 2679) - Definite TB cases only (n = 40).
| Variable | Description | n (col %) | Rate/1000 pyrs | TB cases/pyrs | Unadjusted HR(95% CI) | P-value |
| TST response1 (mm) | <10≥ 10 | 867 (35)1591 (65) | 3.269.00 | 6/184030/3332 | 12.73 (1.14–6.56) | 0.013 |
| TST response 1 (mm) | <55–9.910–14.9≥ 15 | 548 (22)319 (13)688 (28)903 (37) | 2.514.652.7713.76 | 3/19513/6454/144326/1889 | 11.73 (0.35–8.57)1.06 (0.24–4.73)5.31 (1.61–17.53) | 0.0002 |
| EC response2(SFC/Million PBMC) | <20≥ 20 | 337 (35)615 (65) | 4.1111.30 | 3/73015/1327 | 12.75 (0.80–9.50) | 0.076 |
| EC response2(SFC/Million PBMC) | <32≥ 32 | 408 (43)544 (58) | 3.4312.68 | 3/87515/1183 | 13.76 (1.09–13.00) | 0.017 |
| Gender | MaleFemale | 1420 (53)1259 (47) | 6.847.39 | 18/263022/2977 | 11.08 (0.58–2.01) | 0.81 |
| Age (years) | ≤1516–29≥ 30 | 1031 (38)897 (33)751 (28) | 1.8012.028.97 | 4/221622/1830141560 | 16.46 (2.23–18.76)4.86 (1.60–14.76) | 0.0001 |
| Proximity to index case at night2 | Other houseSame houseSame roomSame bed | 430 (16)1764 (66)213 (8)271 (10) | 4.815.0411.221.30 | 4/83119/37665/44412/563 | 11.15 (0.39–3.39)2.54 (0.68–9.47)4.80 (1.54–14.88) | 0.0001 |
1
n = 221 missing;
2
based on n = 952; pyrs = person years; HR = hazard ratio; CI = confidence interval; CXR = chest radiograph; col = column; nmax = maximum number.