Table 5. Multivariable analysis of time to TB episode (all TB cases and definite TB cases only); unadjusted and adjusted hazard ratios, 95% CI and P-values, separately for TST and EC responses.
Variable | n | Unadjusted HR | Adjusted HR1(95% CI) | P-value | |
All TB cases (n = 52) | |||||
TST response (mm) | <10≥ 10 | 2458 | 12.37 | 11.55 (0.74–3.24) | 0.23 |
TST response (mm) | <55–910–14≥ 15 | 2458 | 12.181.404.92 | 11.27 (0.34–4.82)0.73 (0.21–2.56)2.56 (0.88–7.41) | 0.005 |
EC response(SFC/million PBMC) | <32≥ 32 | 951 | 12.13 | 11.98 (0.77–5.08) | 0.14 |
Definite TB cases (n = 40) | |||||
TST response (mm) | <10≥ 10 | 2458 | 12.73 | 11.73 (0.71–4.23) | 0.20 |
TST response (mm) | <55–910–14≥ 15 | 2458 | 11.731.065.31 | 10.94 (0.19–4.72)0.52 (0.11–2.36)2.58 (0.76–8.74) | 0.003 |
EC response(SFC/million PBMC) | <32≥ 32 | 951 | 13.77 | 13.61 (1.03–12.65) | 0.02 |
adjusted for sex, age group, proximity to index case.
HR = hazard ratio; CI = confidence interval.