Figure 1. Schematic of model.
In our model the density of the parasite, , depends on two factors – its own replication (at rate
) and its clearance by activated innate immune cells
at rate
. The total number of innate immune cells equals
and they can be either in a resting or activated state. Since
is the number of activated cells, the number of resting cells equals
. Resting innate immune cells are activated at rate
, and revert back to the inactive state at exponential rate
.