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. Author manuscript; available in PMC: 2010 May 6.
Published in final edited form as: Integr Biol (Camb). 2009 Feb 26;1(4):301–310. doi: 10.1039/b900685k

Fig. 3.

Fig. 3

SNARE perturbations suppress the observed facilitation of membrane fusion. An upward shift in the fusion force spectrum (DFS) was observed upon cleavage of VAMP 2 in the v-SNARE bilayers or substitution of SNAP-25 with mutant forms in the t-SNARE bilayers. Such shift in the DFS is due to the increased compression force that is required to induce bilayer hemifusion and is indicative of the increased overall energy requirements for membrane fusion pursuant to the SNARE perturbations in our experimental system. Lines are fits of eqn (1) to the data points. Error bars are the s.e.m. (33 < n < 289).