. Author manuscript; available in PMC: 2010 May 6.

Published in final edited form as: Integr Biol (Camb). 2009 Feb 26;1(4):301–310. doi: 10.1039/b900685k

Table 1.

Energy barrier parameters for the fusion of the bilayers and the dissociation of the SNARE complex

Bilayer	x_β1/Å	$k_{β 1}^{o}$ /s⁻¹	x_β2/Å	$k_{β 2}^{o}$ /s⁻¹	x_ϕ/Å	$k_{ϕ}^{o}$ /s⁻¹
SNARE-free	N/A	N/A	N/A	N/A	0.31	10.57
v-/t-SNAREs	0.17	7.65	1.59	0.29	0.85	22.5
v-/t-SNAREs (No SNAP25)	0.40	8.47	1.70	0.39	0.52	10.22
v-/t-SNAREs (mut1-SNAP25)	0.97	15.6	3.18	0.21	0.37	7.74
v-/t-SNAREs (mut2-SNAP25)	0.46	14.3	2.17	0.34	0.47	5.97
v-/t-SNAREs (BoNT/B)	0.37	20.1	2.32	0.46	0.53	19.14

k° is the dissociation rate of the activation barrier for fusion (ϕ) and unbinding (β), and the indices, 1 and 2, refer to the inner and outer barrier, respectively. x describes the width of the energy barrier during fusion (ϕ) and unbinding (β).