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. Author manuscript; available in PMC: 2011 May 13.
Published in final edited form as: J Med Chem. 2010 May 13;53(9):3632–3644. doi: 10.1021/jm1000612

Table 3.

Average body weights of athymic nude mice treated with citrate, 19, and irinotecan.

Average body weight ± standard deviation (g)
Day Citrate Compd 19 Irinotecan
17 22.0 ± 1.8 19.7 ± 1.9 19.5 ± 1.3
24 22.5 ± 1.5 20.2 ± 2.3 19.8 ± 1.4
31 23.9 ± 1.0 20.9 ± 2.4 18.4 ± 2.0a
35 24.6 ± 1.3b 21.1 ± 1.9 20.7 ± 1.6
a

One cage of four mice was found not to have a water bottle, which is reflected the drop in average weight on day 31.

b

One mouse was euthanized on day 31 because the tumor volume was 2,266 mm3, which exceeded protocol limitations.