Table 3.
Average body weight ± standard deviation (g) | |||
---|---|---|---|
Day | Citrate | Compd 19 | Irinotecan |
17 | 22.0 ± 1.8 | 19.7 ± 1.9 | 19.5 ± 1.3 |
24 | 22.5 ± 1.5 | 20.2 ± 2.3 | 19.8 ± 1.4 |
31 | 23.9 ± 1.0 | 20.9 ± 2.4 | 18.4 ± 2.0a |
35 | 24.6 ± 1.3b | 21.1 ± 1.9 | 20.7 ± 1.6 |
One cage of four mice was found not to have a water bottle, which is reflected the drop in average weight on day 31.
One mouse was euthanized on day 31 because the tumor volume was 2,266 mm3, which exceeded protocol limitations.