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(A) A diagram shows the chemical structure of muscone (3-methylcyclopentadecanone). (B) IL-1β (0–20 ng/mL) inhibits the viability of end-plate chondrocytes in a dose-dependent manner. (C) Muscone alone does not have any effect on the viability of end-plate chondrocytes. (D) Muscone blocked the IL-1β-induced cytotoxic effects in a dose-dependent manner. Values are shown as means (bars) + SDs (error bars) of three independent experiments. OD = optical density.
