Table.
Case-control studies on primary and secondary multidrug resistant tuberculosis, France, 1992-4
| Characteristic | No (%) of patients with primary multidrug resistant tuberculosis (n=31) | No (%) of new cases of tuberculosis | Adjusted odds ratio (95% CI) | No (%) of patients with secondary multidrug resistant tuberculosis | No (%) of patients with recurrent tuberculosis | Adjusted odds ratio (95% CI) | |
|---|---|---|---|---|---|---|---|
| Sex: | |||||||
| Female | 10 (32) | 4 161 (37) | Reference | 21 (23) | 740 (35) | Reference | |
| Male | 21 (68) | 6 994 (62) | 1.0 (0.5 to 2.0) | 70 (77) | 1382 (65) | 1.5 (0.9 to 2.5) | |
| Age group (years): | |||||||
| 45+ | 8 (26) | 4 910 (44) | Reference | 37 (41) | 1492 (70) | Reference | |
| 0-44 | 23 (74) | 6 235 (56) | 1.5 (0.6 to 3.4) | 54 (59) | 627 (30) | 2.2 (1.4 to 3.5) | |
| Geographic origin: | |||||||
| Europe | 17 (55) | 8 012 (76) | Reference | 46 (51) | 1688 (84) | Reference | |
| North Africa | 5 (16) | 1 057 (10) | 2.5 (0.9 to 6.8) | 16 (18) | 186 (9) | 2.7 (1.5 to 4.9) | |
| Sub-Saharan/other | 9 (29) | 1 468 (14) | 2.4 (1.0 to 5.5) | 28 (31)* | 142 (7) | 4.8 (2.8 to 8.2) | |
| HIV status: | |||||||
| Negative/unknown | 20 (64) | 10 267 (92) | Reference | 79 (83) | 2015 (95) | Reference | |
| Positive | 11 (36) | 893 (8) | 5.6 (2.6 to 12.1)† | 12 (17) | 107 (5) | 1.6 (0.8 to 3.1)‡ | |
| Total | 31 (100) | 11 160 (100) | 91 (100) | 2122 (100) |
*
Country of birth was unknown for one patient.
†
When only patients with known HIV status were included (29 multidrug resistant tuberculosis, 5864 new cases), the adjusted odds ratio for HIV positivity was 3.3 (1.5 to 7.3).
‡
When only patients with known HIV status were included (69 multidrug resistant tuberculosis, 868 recurrent cases), the adjusted odds ratio for HIV positivity was 1.0 (0.5 to 2.0).