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Relative difference in SASA per residue (% of SASA difference) between L55P-TTR and WT-TTR, across all sampled conformations. The secondary structure motifs in native TTR are identified by eight black rectangles corresponding to the beta-strands, and a gray rectangle corresponding to the alpha-helix. Additionally, residue 55 and all other residues displaying exceptionally high SASA increases are labeled.
