Table 4. Predictor variables for high anxiety and psychological distress at biopsy, after receiving a negative biopsy result, and 12 weeks later.

		Anxietya		Distressb
Predictor	Time-point	N	OR (CI)	P-value	N	OR (CI)	P-value
Baselinec tense/anxious mood	(2) Biopsy	90	1.34 (1.12–1.61)	0.001	86	1.13 (0.98–1.30)	0.09
	(3) Post-negative result	122	1.37 (1.16–1.62)	<0.001	117	1.03 (0.91–1.16)	0.65
	(4) After 12 weeks	93	1.55 (1.13–2.13)	0.007	93	1.16 (0.95–1.43)	0.15
Baselinec intrusive thoughts	(2) Biopsy	90	1.53 (1.16–2.01)	0.002	87	1.43 (1.11–1.85)	0.006
	(3) Post-negative result	122	1.43 (1.17–1.74)	0.001	119	1.17 (1.00–1.36)	0.049
	(4) After 12 weeks	94	1.21 (0.98–1.48)	0.07	96	1.21 (1.00–1.45)	0.047
Baselinec avoidant behaviours	(2) Biopsy	85	1.29 (1.07–1.55)	0.008	82	1.23 (1.03–1.48)	0.02
	(3) Post-negative result	115	1.31 (1.09–1.57)	0.004	113	1.29 (1.06–1.57)	0.01
	(4) After 12 weeks	91	1.06 (0.79–1.42)	0.71	93	1.08 (0.86–1.36)	0.50

Abbreviations: CI=95% confidence interval; OR=odds ratio; PSA=prostate-specific antigen.

^aBased on Profile of Mood State tension-anxiety score.

^bBased on Impact of Events Scale total score.

^cBaseline mood and distress is that measured at time of initial PSA testing.