Table 1.

Example of entropy calculation from protein-protein interaction data for a gene pair.

Module state	Gene 1 state	Gene 2 state	N0	N1	H
[0 0]	0	0	28	27	0.9998
[1 0]	1	0	1	50	0.1396
[0 1]	0	1	30	16	0.9321
[1 1]	1	1	23	5	0.6769

N₀, number of times that the state S appeared in normal samples. N₁, the number of times it appeared in cancerous samples. H, Entropy.