Table 5.
KEGG pathway enriched in gene signatures.
| Term | Count | % | P valueb | Genes |
|---|---|---|---|---|
| MAPK SIGNALING PATHWAY | 17 | 9.09 | 1.07E-04 | TRAF6, IKBKG, TP53, GADD45B, AKT3, MAP3K1, MAP3K3, HRAS, CHUK, MAP3K14, NFKB2, EGFR, MAP3K7IP1, TNFRSF1A, IKBKB, PRKCG, IKBKE, |
| FOCAL ADHESION | 14 | 7.49 | 3.62E-04 | CTNNB1, BCL2, SRC, AKT3, CAV2, HRAS, ERBB2, CAV1, FYN, EGFR, LAMB2, PRKCG, SHC1, VCL, |
| APOPTOSIS | 12 | 6.42 | 1.98E-06 | BCL2L1, MAP3K14, CHUK, IKBKG, BCL2, TP53, NFKB2, AKT3, IKBKB, TNFRSF1A, IRAK1, TRADD, |
| CELL CYCLE | 12 | 6.42 | 1.35E-05 | YWHAZ, CDK2, CDKN1A, MAD2L1, SFN, PCNA, TP53, SMAD3, GADD45B, CCNE1, CREBBP, MCM6, |
| ADHERENS JUNCTION | 11 | 5.88 | 3.61E-06 | TJP1, CTNNB1, ERBB2, INSR, FYN, SMAD3, SRC, EGFR, PARD3, CREBBP, VCL |
b
P Value is calculated by DAVID tool.