Fig. 1.

Effect of Jeju seaweed extracts on nitric oxide production in LPS-stimulated RAW 264.7 cells

The cells were stimulated with 1 µg/ml of LPS only or with a combination of LPS and various concentrations (3.125, 12.5, 25, or 50 µg/ml) of seaweed varieties JBR510 (a), JBR511 (b), JBR518 (c), JBR538 (d), and JBR375 (e) for 24 h. Nitric oxide production was determined by the Griess reagent method. Cell viability was determined using the 24-h culture of cells stimulated with LPS (1 µg/ml) in the presence of each sample. The data represent the mean±SD of triplicate experiments. ^* P<0.05, ^** P<0.01 vs. LPS alone