Table 1.

Expression of MHC Class II and Co-Stimulatory Proteins in Eosinophils: Key Evidence

Author	Organism	Description
MHC Class II
Lucey et al 5	Human	GM-CSF stimulates HLA-DR expression
Sedgwick et al 6	Human	Airway eos express HLA-DR in allergic subjects after segmental allergen challenge
Hansel et al 7	Human	Sputum eos from asthmatics express HLA-DR
Mawhorter et al 8	Mouse	Peritoneal eos express MHC Class II in infection with Brugia malayi
Yamamoto et al 9	Human	Eos migrating through an endothelial cell layer express HLA-DR
MacKenzie et al 12	Mouse	Eos from allergen-challenged lung express MHC Class II
Shi et al 13	Mouse	Eos from allergen-challenged lung express MHC Class II
Duez et al 17	Mouse	Lymph node eos in allergen challenged mice express MHC Class II
Wang et al 18	Mouse	Eos from IL-5 transgenic mice express HLA-DR
Padigel et al 19	Mouse	Eos pulsed with Strongyloides antigen upregulate MHC Class II
CD40
Ohkawara et al 11	Human	Eos from allergic nasal mucosa express CD40
Wang et al 18	Mouse	Eos from IL-5 transgenic mice express CD40
CD80, CD86
MacKenzie et al 12	Mouse	Eos from allergen-challenged lung express CD80, CD86
Shi et al 13	Mouse	Eos from allergen-challenged lung express CD80, CD86
Tamura et al 14	Mouse	Eos from IL-5 tansgenic mice express CD80, CD86
Woerly et al 15	Human	Eos from hypereosinophilic patients express CD86, CD28
Celestin et al 16	Human	IL-3 stimulates CD86 expression in eos
Duez et al 17	Mouse	Lymph node eos in allergen challenged mice express CD80, CD86
Wang et al 18	Mouse	Eos from IL-5 transgenic mice express CD80, CD86
Padigel et al 19	Mouse	Eos pulsed with Strongyloides antigen upregulate CD86

Abbreviations: eos = eosinophils