Figure 3.

Global PLS-DA scores (A) and loadings line plots for discriminatory components 2 and 3 (B) from plasma ¹H NMR spectral data showing differentiation of the samples from noninfected control animals (black) and the 3 parasite-mouse models; S. mansoni (red), T. b. brucei (green), and P. berghei (blue). The protozoan infections are clearly differentiated from the noninfected and S. mansoni-infected groups along the first PC, while S. mansoni is differentiated from all other groups in the second PC. (C) PCA scores plot and (D) loadings plots derived from relative cytokine levels from matched animals from each infection model.