Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Jan 6;30(1):230–241. doi: 10.1523/JNEUROSCI.3995-09.2010

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2010 the authors 0270-6474/10/300230-12$15.00/0

PMC Copyright notice

Figure 7. — Spike frequency adaptation and changes in gain by added conductance correlate with decreased Na⁺ conductance availability. A, Example of a voltage trace showing spike frequency adaptation that was generated in response to a 4 s current step under control conditions (i). Plot of average normalized spike frequency as a function of ISI number (ii). B, Example of a membrane voltage derivative trace generated in response to a 4 s current step (same cell as shown in Ai). Plot of average normalized spike rate of rise for spikes generated at steady state as a function of ISI number under control conditions (ii). C, Examples of spike voltage trajectories generated at an approximate steady-state firing frequency of 5 Hz under control and with 5, 10, and 15 nS of added conductance (i). Plot of average normalized rate of rise for steady-state spikes as a function of added conductance (ii). D, Examples of spike voltage trajectories taken from the initial spike under control and with 5, 10, and 15 nS of added conductance (i). Plot of average normalized rate of rise for initial spikes as a function of added conductance (ii).