Figure B1.—
The diagrammed process shows the number of haploid cells (H) increases by growth (μH) and when a duplication-bearing cell loses its duplication (μDkL). Haploid cells can be lost when a duplication arises (μHkF). Duplication cell number (D) increases by growth (μD) and when a duplication forms in a haploid cell (μHkF). Duplications can be lost by reversion (i.e. recombination between repeats) as diagrammed in Figure 2 (μDkL). The duplication frequency (R = D/H) rises to a steady state (R∞) at which point the difference between duplication formation and loss is balanced by the differences between diploid and haploid growth rates.