TABLE 3.
Multilocus HKA test involving the HBB-T1 and HBB-T2 genes and eight reference loci
Polymorphism |
Divergence |
||||||||
---|---|---|---|---|---|---|---|---|---|
Locus | Chromosome | I | θ (2.5–97.5%) | S/ES | Var | Dev | D/ED | Var | Dev |
HBB-T1 | 7 | 1.00 | 0.0056 (0.0038–0.0084) | 57/45.46 | 215.82 | 0.618 | 44/55.54 | 126.82 | 1.051 |
HBB-T2 | 7 | 1.00 | 0.0082 (0.0056–0.0119) | 118/65.39 | 417.90 | 6.624 | 44/96.61 | 312.25 | 8.865 |
Chrng | 1 | 1.00 | 0.0059 (0.0040–0.0093) | 61/55.44 | 308.90 | 0.100 | 42/47.56 | 99.80 | 0.309 |
Med19 | 2 | 1.00 | 0.0057 (0.0039–0.0082) | 15/44.05 | 193.69 | 4.358 | 92/62.95 | 154.48 | 5.464 |
Prpf3 | 3 | 1.00 | 0.0032 (0.0021–0.0046) | 31/35.25 | 132.57 | 0.136 | 55/50.75 | 110.25 | 0.164 |
Clcn6 | 4 | 1.00 | 0.0058 (0.0039–0.0082) | 54/52.68 | 270.00 | 0.006 | 75/76.32 | 210.89 | 0.008 |
G6pdx | X | 0.75 | 0.0037 (0.0025–0.0053) | 19/26.35 | 95.43 | 0.567 | 63/55.65 | 99.13 | 0.545 |
Orc1 | X | 0.75 | 0.0056 (0.0038–0.0081) | 32/31.89 | 141.81 | 0.000 | 68/68.11 | 133.26 | 0.000 |
Jarid 1d | Y | 0.25 | 0.0072 (0.0049–0.0105) | 4/13.56 | 40.99 | 2.232 | 68/58.44 | 64.72 | 1.413 |
Control region | mtDNA | 0.25 | 0.0598 (0.0438–0.0803) | 33/53.93 | 338.90 | 1.292 | 329/308.07 | 482.64 | 0.907 |
χd.f.=92 = 34.661, P = 0.00007. I, inheritance scalar (1.00 for autosomal loci, 0.75 for X-linked loci and 0.25 for the Y-linked locus and mtDNA); S, observed number of segregating sites; ES, expected number of segregating sites; Var, variance under the model; Dev, deviation of each observed value from the model-based expectation; D, observed divergence to M. caroli; and ED, expected divergence.