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. Author manuscript; available in PMC: 2010 May 10.
Published in final edited form as: Circ Heart Fail. 2010 Jan 27;3(2):294–305. doi: 10.1161/CIRCHEARTFAILURE.109.903450

Figure 6.

Figure 6

BFT stimulates prosurvival signaling in type 1 DM. Representative blots (A) and bar graphs (B through I) showing the levels of pAkt, peNOS, pFOXO-1, pSTAT3, Pim-1, pBad, Bcl-2, and cleaved caspase-3 (n=4 per group). Bar graphs showing myocardial Akt activity (J). Representative immunoblots and bar graphs showing O-GlcNAc modification of Akt in diabetic hearts (K) (n=4 per group). Values are expressed as n-fold changes toward age-matched healthy controls. STZ indicates streptozotocin. Siegel-Tukey test detected statistical differences as follows: *P<0.01 and **P<0.001 versus healthy controls; #P<0.01 and ##P<0.001 versus vehicle-treated diabetic mice.