Table 1.
SNP | Location | r2 with rs104865 67 |
Risk allele freq. | χ2 statistics | 1p-value | Heterozygous | Homozygous | |||
---|---|---|---|---|---|---|---|---|---|---|
(Risk allele) | Controls | Cases | OR | 95% CI | OR | 95% CI | ||||
rs10486567 (G) | 27,943,088 | -- | 0.759 | 0.788 | 46.55 | 7.79 × 10−11 | 1.19 | 1.12–1.27 | 1.37 | 1.20–1.56 |
rs10807843 (T) | 27,958,915 | 0.893 | 0.777 | 0.805 | 43.88 | 2.96 × 10−10 | 1.2 | 1.12–1.27 | 1.35 | 1.17–1.56 |
rs38504 (C) | 27,982,859 | 0.463 | 0.79 | 0.812 | 26.54 | 1.73 × 10−6 | 1.17 | 1.10–1.24 | 1.18 | 1.02–1.36 |
Results for top 3 JAZF1 SNPs of 106 tested.
p-values are for genotype association test (additive model) adjusted for study and significant principal components (see Supplementary Methods).