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Pretreatment with 0.03 mg/kg 8-OH-DPAT reverses the attenuation of the cocaine priming effect induced by A) 0.3 mg/kg spiradoline and B) 5.6 mg/kg fluoxetine but does not alter C) cocaine priming. Data are means ± S.E.M. from four monkeys. * indicates significant differences compared to cocaine priming (p < 0.05). C = cocaine, S = spiradoline, D = 8-OH-DPAT, F = fluoxetine.
