Table 2.

Effects of control antidepressants on immobility time in the automated mouse forced swim test and locomotor activity.

Treatment	Immobility Time (sec)	Locomotor Activity
Vehicle
	120.5 ± 7.37	1618 ± 142
Fluoxetine (mg/kg)
10	90.8 ± 10.00	1898 ± 132
20	90.4 ± 6.82	1293 ± 243
40	75.8 ± 12.89 **	143 ± 34 ***
Desipramine (mg/kg)
10	111.8 ± 6.63	763 ± 112 **
20	81.44 ± 4.93 **	776 ± 265 **
40	70.30 ± 8.91 ***	117 ± 43 ***

Values are mean ± SEM. n = 7–10 per group.

^**p < 0.01,

^***p < 0.001 versus control (0 mg/kg) (ANOVA followed by Dunnett’s posthoc test)