Table 2. Diabetes Management by Treatment Group During the DCCT/EDIC and EDC Studies.
| Conventional |
Intensive |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| DCCT |
EDIC |
EDC |
DCCT |
EDIC |
|||||||
| Diabetes Management |
Year 1 (n=730) |
Closeout (n=723) |
Year 6 (n=660) |
Year 12 (n=606) |
Year 1 (n=161) |
Year 10 (n=105) |
Year 18 (n=88) |
Year 1 (n=711) |
Closeout (n=698) |
Year 6 (n=654) |
Year 12 (n=620) |
| Insulin delivery, % | |||||||||||
| CSII | 0.1 | 1.5 | 22.6 | 45.2 | 2.5 | 6.7 | 38.6 | 29.8 | 41.4 | 37.9 | 48.4 |
| MDI | 1.0 | 3.6 | 57.4 | 49.3 | 4.3 | 36.2 | 37.5 | 70.0 | 56.0 | 56.8 | 48.9 |
| 1-2 Injections | 98.9 | 94.9 | 19.4 | 5.1 | 89.4 | 53.4 | 15.9 | 0.3 | 2.6 | 5.1 | 2.1 |
| Insulin dose, mean (SD), U/kg/d |
0.68 (0.25) | 0.66 (0.20) | 0.67 (0.21) | 0.64 (0.25) | 0.90 (0.25) | 0.75 (0.22) | 0.72 (0.22) | 0.73 (0.26) | 0.71 (0.24) | 0.73 (0.25) | 0.68 (0.27) |
| Self-monitoring blood glucose, % (≥4 times/d) |
1.7 | 3.7 | 43.5 | 63.7 | NA | 23.8 | 46.6 | 69.1 | 52.9 | 47.1 | 56.1 |
Abbreviations: CSII, continuous subcutaneous insulin infusion (external insulin pump); DCCT, Diabetes Control and Complications Trial; EDC, Pittsburgh Epidemiology of Diabetes Complications Experience; EDIC, Epidemiology of Diabetes Interventions and Complications; MDI, multiple (≥3) daily injection therapy; NA, not applicable.