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. Author manuscript; available in PMC: 2010 May 10.
Published in final edited form as: J Nucl Med. 2010 Jan 15;51(2):183–192. doi: 10.2967/jnumed.109.066159

Table 2.

M1 M2a M2b M3 Model 1 parameter values Model 2a parameter values SUVbw
max
Pat # scan tumor BIC BIC BIC BIC V ktrap bound
fraction		 V k1 k2 ktrap Ki bound
fraction		 30 min
pi
1 pre 1 1.20 1.27 1.29 1.29 0.050 (0.031) 0.115 (0.004) 0.95 0.033 (0.032) 0.126 (0.008) 0.004 (0.003) 0.000 (0.000) 0.000 0.00 8.0
1 post1 1 0.94 1.03 1.02 1.17 0.027 (0.029) 0.074 (0.004) 0.96 0.000 (0.000) 0.199 (0.237) 1.507 (4.246) 0.952 (0.994) 0.077 0.99 4.5
1 post 2 1 0.32 0.42 0.51 0.65 0.001 (0.015) 0.037 (0.002) 1.00 0.000 (0.000) 0.042 (0.007) 0.015 (0.041) 0.078 (0.211) 0.035 0.78 2.3
2 pre 1 2.16 2.29 2.28 2.43 0.042 (0.066) 0.120 (0.009) 0.96 0.000 (0.000) 0.237 (0.347) 0.763 (3.779) 0.829 (1.783) 0.124 0.99 11.2
2 post 1 1.35 1.28 1.37 1.52 0.010 (0.035) 0.096 (0.005) 0.99 0.000 (0.000) 0.138 (0.023) 0.073 (0.074) 0.154 (0.102) 0.093 0.93 6.8
3 pre 1 2.09 1.29 1.86 2.00 0.185 (0.090) 0.036 (0.011) 0.63 0.000 (0.000) 0.166 (0.017) 0.080 (0.016) 0.018 (0.006) 0.031 0.47 3.3
4 pre 1 0.88 0.91 0.77 0.83 0.027 (0.006) 0.090 (0.002) 0.97 0.017 (0.010) 0.139 (0.051) 0.259 (0.507) 0.467 (0.506) 0.089 0.96 6.6
4 pre 2 1.78 1.87 1.83 1.80 0.054 (0.022) 0.063 (0.005) 0.91 0.025 (0.047) 0.210 (0.292) 0.828 (2.228) 0.364 (0.382) 0.064 0.93 5.5
4 post 1 1.10 1.25 1.22 1.33 0.045 (0.018) 0.103 (0.004) 0.95 collapsed to model 1 5.5
4 post 2 1.04 1.15 1.21 1.31 0.138 (0.032) 0.070 (0.005) 0.81 0.125 (0.037) 0.083 (0.022) 0.013 (0.044) 0.032 (0.216) 0.058 0.41 4.5
5 post 1 0.71 0.79 0.84 0.98 0.054 (0.014) 0.054 (0.003) 0.90 0.040 (0.020) 0.100 (0.068) 0.304 (0.775) 0.360 (0.478) 0.054 0.90 3.1
5 post 2 0.60 0.74 0.64 0.81 0.111 (0.020) 0.055 (0.003) 0.81 collapsed to model 1 3.3
5 post 1 0.61 0.67 0.78 1.20 0.000 (0.019) 0.078 (0.003) 0.81 0.000 (0.000) 0.09 (0.003) 0.01 (0.002) 0.00 (0.000) 0.000 0.90 4.5
5 post 2 0.90 0.94 1.10 1.80 0.005 (0.005) 0.026 (0.002) 0.81 0.000 (0.000) 0.05 (0.011) 0.11 (0.014) 0.12 (0.014) 0.024 0.90 1.6
6 pre 1 1.55 1.70 1.77 1.92 0.267 (0.032) 0.074 (0.005) 0.70 collapsed to model 1 10.1
6 pre 2 1.25 1.28 1.44 1.58 0.200 (0.017) 0.094 (0.003) 0.80 0.189 (0.018) 0.106 (0.010) 0.008 (0.015) 0.012 (0.129) 0.062 0.19 11.0
6 pre 3 1.67 1.81 1.76 1.89 0.227 (0.041) 0.059 (0.006) 0.69 collapsed to model 1 8.1
7 post 2 1 2.28 1.64 1.73 2.18 0.179 (0.101) 0.120 (0.014) 0.85 0.002 (0.055) 0.276 (0.032) 0.073 (0.022) 0.045 (0.016) 0.106 0.71 8.2
8 pre 1 1.13 0.17 0.80 0.94 0.057 (0.031) 0.054 (0.004) 0.89 0.006 (0.012) 0.092 (0.006) 0.035 (0.009) 0.022 (0.014) 0.036 0.43 3.5
8 post 1 1.78 1.62 1.79 1.94 0.000 (0.000) 0.183 (0.003) 1.00 0.000 (0.000) 0.241 (0.026) 0.040 (0.032) 0.097 (0.062) 0.170 0.86 11.5
9 pre 1 1.71 1.83 1.78 1.92 0.080 (0.042) 0.032 (0.006) 0.77 0.065 (0.046) 0.041 (0.012) 0.013 (0.013) 0.000 (0.000) 0.000 0.00 3.1
9 post 1 1.79 1.17 1.45 1.59 0.093 (0.050) 0.041 (0.007) 0.79 0.000 (0.000) 0.209 (0.037) 0.381 (0.129) 0.109 (0.021) 0.046 0.91 4.1
10 pre 1 1.74 1.88 1.85 1.99 0.009 (0.043) 0.036 (0.006) 0.97 0.004 (0.048) 0.039 (0.012) 0.005 (0.014) 0.000 (0.000) 0.000 0.00 3.1
10 post 1 1.99 1.98 2.04 1.96 0.119 (0.054) 0.088 (0.007) 0.86 0.077 (0.052) 0.115 (0.014) 0.014 (0.005) 0.000 (0.000) 0.000 0.00 7.9
11 pre 1 1.49 1.03 1.60 1.19 0.063 (0.029) 0.070 (0.004) 0.90 0.022 (0.019) 0.100 (0.009) 0.022 (0.012) 0.021 (0.031) 0.048 0.38 7.2
11 post 1 1.18 1.09 1.05 1.19 0.153 (0.032) 0.031 (0.004) 0.63 0.053 (0.066) 0.290 (0.306) 1.444 (1.695) 0.236 (0.066) 0.041 0.84 3.2
12 pre 1 no FDHT uptake therefore excluded from further analysis
13 pre 1 no FDHT uptake therefore excluded from further analysis

Units for ktrap, k1, k2 and Ki are all 1/minutes. The V parameters are unit-less, as are the bound-fraction and SUVbw. Bolded and italicized BIC values are the minimums for the corresponding. The values in (parenthesis) are standard deviations.