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. 1998 Sep 12;317(7160):720–726.

Table 5.

Incremental cost effectiveness of policy of tight control of blood pressure compared with less tight control. Means (95% confidence intervals) calculated with Fieller’s method, costs based on 1997 values

Cost and outcome measure Costs and health effects discounted
Costs only discounted
6% discount 3% discount 6% discount 3% discount
Time free from diabetes related end points:
 Costs for standard practice 1049 (−4635 to 52 373)   599 (−3400 to 13 226) 434 (−1663 to 6255) 390 (−2086 to 6255)
 Costs driven by trial protocol* −333 (−10 767 to 23 882) NA NA NA
Life years gained**:
 Costs for standard practice  720 422 291 261
 Costs driven by trial protocol* −229 NA NA NA

NA=Not applicable. 

*

Negative ratios costs indicate tight control is both more effective and cost saving. 

**

Estimated life years gained from tight control were not significant at 5% level (see table 4), hence 95% confidence intervals cannot be defined.