TABLE 4.

Predictors of the discrepancy between vasomotor symptom frequency and bother

Hot flashes, OR (95% CI)		Night sweats, OR (95% CI)
Low frequency/high bothera,b		Low frequency/high bothera,c
Race/ethnicity		Poorer self-rated healthd	1.33 (1.02–1.74)i
African	2.40 (1.32–4.37)j	Sleep problems	1.26 (0.98–1.63)h
American
Chinese	0.84 (0.33–2.17)
Japanese	0.34 (0.13–0.89)i
White	Reference
Education
≤ High school	1.53 (1.07–2.19)i
Some college/vocational	0.80 (0.58–1.11)
≥College	Reference
Poorer self-rated healthd	1.43 (1.06–1.92)i
High frequency/low bothere,g		High frequency/low bothere,f
Negative affectd	0.71 (0.51–0.98)i	Sleep problems	0.79 (0.62–1.00)h
Marital status		Marital status
Married	1.34 (0.98–1.83)h	Married	1.26 (0.98–1.63)h
Unmarried	Reference	Unmarried	Reference
		Menopausal status
		Pre-/early perimenopausal	Reference
		Late perimenopausal	0.52 (0.31–0.88)i
		Postmenopausal/indeterminate	0.99 (0.70–1.40)

Low frequency, 3 or fewer hot flashes per week and 2 or fewer night sweats per week; high frequency, 12 or more hot flashes per week; 3 or more night sweats per week; low bother: none (1), a little (2); high bother, moderate (3), a lot (4).

^aReference: low frequency/low bother.

^bCovariates: age, site, body mass index, menopausal status, race/ethnicity, education, sleep problems, negative affect, self-rated health.

^cCovariates: site, sleep problems, self-rated health.

^dOR associated with every 1 SD increase.

^eReference: high frequency/high bother.

^fCovariates: site, menopausal status, marital status, sleep problems, negative affect, self-rated health, symptom sensitivity.

^gCovariates: age, site, body mass index, race/ethnicity, education, marital status, sleep problems, negative affect, self-rated health.

^hP < 0.10;

ⁱP < 0.05;

^jP < 0.01.