Table 1.
Monkey | Histomorphometric Optic Disc Size $ | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | ID | Weight (kg) | Age (y) | Species | Sex | Eye | IOP# (mm Hg) | Fixation Pressure (mm Hg) | Axial Length (mm) | Duration of IOP elevation (min) | Number of serial Section Images | Vertical (μm) & | Horizontal (μm) * | Area (mm2) ! |
1 | 20852 | 4.32 | 14 | Rhesus | Female | Right | 11 | 45 | NA | 15 | 686 | 1214 | 869 | 0.828 |
Left | 11 | 10 | NA | - | 554 | 1216 | 864 | 0.825 | ||||||
2 | 5889 | 5.9 | 6 | Rhesus | Male | Right | 9 | 45 | 20.51 | 15 | 316 | 1415 | 1042 | 1.158 |
Left | 8 | 10 | 20.2 | - | 349 | 1384 | 1009 | 1.097 | ||||||
3 | 7484 | 5.9 | 5 | Rhesus | Male | Right | 9 | 45 | 21.39 | 15 | 283 | 1641 | 1143 | 1.473 |
Left | 8 | 10 | 21.02 | - | 306 | 1577 | 1131 | 1.401 | ||||||
4 | AA3P | 5.5 | 9 | Cynomolgus | Male | Right | 12 | 30 | 18.49 | 15 | 325 | 1238 | 828 | 0.805 |
Left | 12 | 10 | 18.29 | - | 290 | 1263 | 808 | 0.801 | ||||||
5 | 278 | 6 | 5 | Rhesus | Male | Right | 4 | 30 | 19.85 | 15 | 217 | 1534 | 1112 | 1.340 |
Left | 4 | 10 | 19.6 | - | 170 | 1487 | 1073 | 1.253 | ||||||
6 | 528 | 7.2 | 6 | Rhesus | Male | Right | 11 | 30 | 19.89 | 30 | 280 | 1368 | 999 | 1.074 |
Left | 11 | 10 | 18.54 | - | 265 | 1318 | 914 | 0.946 |
Mean IOP of all N = 3 to 9 baseline measurements under ketamine/xylazine anesthesia
Optic disc dimension as determined by the clinical visible optic disc margin which is Neural Canal Opening in these monkey eyes at the perfusion pressure
Vertical length as determined by the major length of the NCO ellipse
Horizontal length as determined by the minor length of the NCO ellipse
Disc Area is determined by the area of the NCO ellipse