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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Jul 23;50(12):5785–5799. doi: 10.1167/iovs.09-3410

Table 2.

Overall Parameter by Monkey

Parameters
Monkey 1
Monkey 2
Monkey 3
Monkey 4
Monkey 5
Monkey 6
PIDmax# Delineation Varibility !
Neural Canal Architecture (μm) Low IOP H-L $ Low IOP H-L Low IOP H-L Low IOP H-L Low IOP H-L Low IOP H-L Inter-D Intra-D1 Intra-D2
NCO Offset
509 1 586 19 663 16 501 −2 633 26 NA NA 9 21 5 4
ASCO Offset
644 −20 676 12 720 14 584 −2 657 9 562 58 16 10 10 12
ALI Offset
645 −20 675 13 720 14 585 1 654 10 569 62 16 8 5 18
PLI Offset
806 −21 797 31 828 13 702 −3 754 25 641 100 18 18 17 6
PSCO Offset
820 −15 825 23 877 −3 735 −5 801 11 658 128 22 24 12 7
ASAS Offset
951 −30 928 11 967 25 888 −16 875 28 781 113 18 14 15 20
ASCO Depth
21 7 54 −4 59 −15 55 −2 40 −7 61 −7 15 6 8 5
ALI Depth
22 6 54 −4 61 −16 57 4 40 −5 70 −1 20 14 6 4
PLI Depth
96 −5 146 −28 142 −11 144 −7 147 1 210 −55 20 13 19 2
PSCO Depth
98 0 159 −38 179 −13 158 −13 200 −26 224 −47 27 23 12 1
ASAS Depth
118 2 179 −54 182 5 167 −25 207 −22 235 −50 25 14 9 6
ONH Connective Tissue (μm)
















Lamina Cribrosa Position
−97 −8 −110 6 −131 11 −134 −6 −70 −7 −126 5 16 18 3 1
Lamina Cribrosa Thickness
90 −2 125 −13 133 −13 128 −12 129 −11 150 −33 16 16 26 15
Peripapillary Scleral Position
2 1 −26 22 −22 12 −28 14 −39 22 −49 17 18 13 7 8
Peripapillary Scleral Thickness
115 15 157 −16 152 11 149 −7 173 8 196 −39 14 38 5 10
Sclera Flange Thickness
58 0 77 −9 94 1 81 4 86 12 NA NA 5 14 12 11
ONH Laminar Cupping
















Post-NCO Total Prelaminar Volume Percent Change((mm3) * 0.126 7.7% 0.145 3.2% 0.223 −8.3% 0.145 10.6% 0.106 16.5% 0.122 18.0% 28.4% 11% NA 2%

Bold: Significant different (P<0.05) by ANOVA.

Grey: Between Eye Difference magnitude achieved statistical significant difference and exceeded the PID maximum (see Methods).

$

Difference between high and low IOP eye.

*

Statistical Analysis is not applicable for this parameter. Percent differences between high and low IOP eyes for this parameter are reported.

#

PIDmax values as previously reported28. Note that in most instances the PIDmax values, which represent how different the parameter is between the two eyes of 6 bilaterally normal monkeys, exceed the full range of the previously reported inter- and intra-delineator varibility24-26.

!

Data were previously reported24-26 inter-delineator (Inter-D) varibility data is the range of varibility in micrometers between five 5 delineators and intra-delineator varibility for two delineators (Intra-D1 and Intra-D2) is the range of varibility in micrometers for each delineator on n=3 delineation days.