Table 2.
Overall Parameter by Monkey
Parameters |
Monkey 1 |
Monkey 2 |
Monkey 3 |
Monkey 4 |
Monkey 5 |
Monkey 6 |
PIDmax# | Delineation Varibility
! |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neural Canal Architecture (μm) | Low IOP | H-L $ | Low IOP | H-L | Low IOP | H-L | Low IOP | H-L | Low IOP | H-L | Low IOP | H-L | Inter-D | Intra-D1 | Intra-D2 | |
NCO Offset
|
509 | 1 | 586 | 19 | 663 | 16 | 501 | −2 | 633 | 26 | NA | NA | 9 | 21 | 5 | 4 |
ASCO Offset
|
644 | −20 | 676 | 12 | 720 | 14 | 584 | −2 | 657 | 9 | 562 | 58 | 16 | 10 | 10 | 12 |
ALI Offset
|
645 | −20 | 675 | 13 | 720 | 14 | 585 | 1 | 654 | 10 | 569 | 62 | 16 | 8 | 5 | 18 |
PLI Offset
|
806 | −21 | 797 | 31 | 828 | 13 | 702 | −3 | 754 | 25 | 641 | 100 | 18 | 18 | 17 | 6 |
PSCO Offset
|
820 | −15 | 825 | 23 | 877 | −3 | 735 | −5 | 801 | 11 | 658 | 128 | 22 | 24 | 12 | 7 |
ASAS Offset
|
951 | −30 | 928 | 11 | 967 | 25 | 888 | −16 | 875 | 28 | 781 | 113 | 18 | 14 | 15 | 20 |
ASCO Depth
|
21 | 7 | 54 | −4 | 59 | −15 | 55 | −2 | 40 | −7 | 61 | −7 | 15 | 6 | 8 | 5 |
ALI Depth
|
22 | 6 | 54 | −4 | 61 | −16 | 57 | 4 | 40 | −5 | 70 | −1 | 20 | 14 | 6 | 4 |
PLI Depth
|
96 | −5 | 146 | −28 | 142 | −11 | 144 | −7 | 147 | 1 | 210 | −55 | 20 | 13 | 19 | 2 |
PSCO Depth
|
98 | 0 | 159 | −38 | 179 | −13 | 158 | −13 | 200 | −26 | 224 | −47 | 27 | 23 | 12 | 1 |
ASAS Depth
|
118 | 2 | 179 | −54 | 182 | 5 | 167 | −25 | 207 | −22 | 235 | −50 | 25 | 14 | 9 | 6 |
ONH Connective Tissue (μm)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lamina Cribrosa Position
|
−97 | −8 | −110 | 6 | −131 | 11 | −134 | −6 | −70 | −7 | −126 | 5 | 16 | 18 | 3 | 1 |
Lamina Cribrosa Thickness
|
90 | −2 | 125 | −13 | 133 | −13 | 128 | −12 | 129 | −11 | 150 | −33 | 16 | 16 | 26 | 15 |
Peripapillary Scleral Position
|
2 | 1 | −26 | 22 | −22 | 12 | −28 | 14 | −39 | 22 | −49 | 17 | 18 | 13 | 7 | 8 |
Peripapillary Scleral Thickness
|
115 | 15 | 157 | −16 | 152 | 11 | 149 | −7 | 173 | 8 | 196 | −39 | 14 | 38 | 5 | 10 |
Sclera Flange Thickness
|
58 | 0 | 77 | −9 | 94 | 1 | 81 | 4 | 86 | 12 | NA | NA | 5 | 14 | 12 | 11 |
ONH Laminar Cupping
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Post-NCO Total Prelaminar Volume Percent Change((mm3) * | 0.126 | 7.7% | 0.145 | 3.2% | 0.223 | −8.3% | 0.145 | 10.6% | 0.106 | 16.5% | 0.122 | 18.0% | 28.4% | 11% | NA | 2% |
Bold: Significant different (P<0.05) by ANOVA.
Grey: Between Eye Difference magnitude achieved statistical significant difference and exceeded the PID maximum (see Methods).
Difference between high and low IOP eye.
Statistical Analysis is not applicable for this parameter. Percent differences between high and low IOP eyes for this parameter are reported.
PIDmax values as previously reported28. Note that in most instances the PIDmax values, which represent how different the parameter is between the two eyes of 6 bilaterally normal monkeys, exceed the full range of the previously reported inter- and intra-delineator varibility24-26.
Data were previously reported24-26 inter-delineator (Inter-D) varibility data is the range of varibility in micrometers between five 5 delineators and intra-delineator varibility for two delineators (Intra-D1 and Intra-D2) is the range of varibility in micrometers for each delineator on n=3 delineation days.