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. Author manuscript; available in PMC: 2010 May 10.
Published in final edited form as: Physiol Genomics. 2007 Jun 19;31(2):203–215. doi: 10.1152/physiolgenomics.00228.2006

Table 5. Partial list of the protein domains identified in the H. glaberrima contigs and their cellular function.

3dpe 7dpe
Normal Domain Normal Cellular Function Domain Cellular Function Domain Cellular Function
FRQ1 signal transduction mechanisms/cytoskeleton/cell division and chromosome partitioning SOUL heme-binding proteins TR-Fer iron ion homeostasis
Euk-ferritin metal ion binding SAA acute-phase response Band-7-prohibitin regulation of apoptosis/histone deacetylation/signal transduction
Epend cell-matrix adhesion EGF-Lam ell adhesion, growth migration, and differentiation vWFA ell adhesion, migration, homing, pattern formation, and signal transduction
Beta-tubulin major components of microtubules A2M endopeptidase inhibitor activity ANK transcription initiation, cell-cycle regulation, cytoskeletal, ion transport and signal transduction
H3 nucleosome assembly/chromosome organization and biogenesis GroEL cellular protein metabolism PP2Cc Intracellular signalling
Ubiquitin ubiquitin conjugating enzyme activity Sec61-beta intracellular protein transport SOUL heme-binding proteins
Cyclophilin-ABH protein folding Fubi tumor suppressor protein COL 1 extracellular matrix structural constituent
WD40 adaptor/regulatory modules in signal transduction, premRNA processing and cytoskeleton assembly TR-Fer iron ion homeostasis NDK nucleoside-diphosphate kinase activity, ATP binding
PCBP-like HK mRNA stabilization, translational activation, and translational silencing nucleoplasmin nucleic acid binding WD40 adaptor/regulatory modules in signal transduction, premRNA processing and cytoskeleton assembly
AhpC posttranslational modification, protein turnover, chaperones RPP1A translation, ribosomal structure and biogenesis FRQ1 Signal transduction mechanisms/Cytoskeleton/Cell division and chromosome partitioning
CT regulate ligand-receptor interactions for a variety of signaling pathways Cox2 cytochrome c oxidase activity TRAP-beta cotranslational protein targeting to membrane
Cox2 cytochrome c oxidase activity Euk-Ferritin metal ion binding Sap B activation of various lysosomal lipid-degrading enzymes
Cox4 cytochrome c oxidase activity RPL30 translation, ribosomal structure and biogenesis Cox2 cytochrome-c oxidase activity
CyoB energy production and conversion ATP-synt-A proton transport NADH5 ATP synthesis coupled electron transport
Rplx translation, ribosomal structure and biogenesis RpsN translation, ribosomal structure and biogenesis Actin structural constituent of cytoskeleton
Oxired-q2 mitochondrial electron transport, NADH to ubiquinone RpsK translation, ribosomal structure and biogenesis RPP1A translation, ribosomal structure and biogenesis
Ribosomal S8 translation, ribosomal structure and biogenesis Cyt-c-oxidase mitochondrial electron transport OSCP ATP synthesis coupled proton transport
Actin structural constituent of cytoskeleton actin structural constituent of cytoskeleton RAMP4 translation, ribosomal structure and biogenesis
RplO translation, ribosomal structure and biogenesis ribosomal-S8 translation, ribosomal structure and biogenesis H2A nucleosome assembly, chromosome organization and biogenesis
NADH5 ATP synthesis coupled electron transport NADHdh electron transport 40S-S3-KH translation, ribosomal structure and biogenesis

Partial list of the most relevant and abundant proteins domains identified in the 3 cDNA libraries.