Table 1.
Cytokine expressed in the ischemic-reperfused and myotoxin-treated muscles at day 7.
| IR+ (% uninjured) | MI+ (% uninjured) | |
|---|---|---|
| Myogenesis | ||
| IGF-I | 71 | 63 |
| IGF-II | 43 | 64 |
| IGFBP-2 | 65 | 65 |
| IGFBP-3 | 107 | 122 |
| IGFBP-5 | 109 | 126 |
| IGFBP-6 | 109 | 110 |
| bFGF | 106 | 97 |
| HGF R | 0 | 19 |
| Angiogenesis | ||
| VEGF | 132 | 113 |
| VEGF R1 | 103 | 138 |
| VEGF R2 | 0 | 0 |
| VEGF R3 | 0 | 0 |
| VEGF-D | 0 | 0 |
| ECM remodelling | ||
| MMP-2 | 65 | 153 |
| MMP-3 | 87 | 52 |
| TIMP-1 | 93 | 85 |
| TIMP-2 | 96 | 73 |
| Pro-MMP-9 | 44 | 48 |
| Chemokines | ||
| Fractalkine | 111 | 90 |
| GCSF | 95 | 91 |
| GM-CSF | 91 | 97 |
| KC (IL8) | 129 | 113 |
| MCP1 | 75 | 85 |
| MCP-5 | 72 | 79 |
| MIP-1_ | 136 | 104 |
| MIP-1_ | 196 | 135 |
| MIP-2 | 146 | 119 |
| MIP-3 _ | 153 | 113 |
| MIP-3_ | 132 | 118 |
| RANTES | 119 | 141 |
| Inflammation | ||
| IL-1 b | 117 | 94 |
| IL-6 | 89 | 69 |
| TNF_ | 107 | 92 |
| sTNF RI | 146 | 94 |
| sTNF RII | 135 | 102 |