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Structure of HPMA copolymer-RGDfK-AH-GDM conjugates. Copolymers P1 and P2 contained the geldanamycin derivative AH-GDM as well as MA-Tyr to label the conjugate with 125I. P1 contained the monocyclized RGDfK peptide targeting moiety to target the αvβ3 integrin.