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. 2010 Mar 31;8(4):1080–1093. doi: 10.3390/md8041080

Table 2.

ACE inhibitory COS derived from marine resources: derivatives and IC50 values.

COS derivative IC50 Ref.
Chitosan trimer 0.9 μM [61]
Chitosan oligosaccharides 1.22 mg/mL [73]
Chitin derivatives
AEC 0.064 μM [74]
AEC 50 0.038 μM [74]
AEC 90 0.103 μM [74]
Aminoethyl-COS (AE-COS) 0.80 μg/mL [75]
Captoprila 0.1 μM [74]
a

positive control