Table 2.
Compound | NOa | NFb | NFc | ARd | ARe | CX1f | CX2g | QRh | QRMSi |
---|---|---|---|---|---|---|---|---|---|
1 | 7 % | 0 % | 23 % | 52 % | 15 % | 24 % | |||
2 | 9 % | 91 % | 15.7 | 65 % | -3 % | -32 % | 29 % | ||
3 | 10 % | 72 % | 24.1 | 58 % | 25 % | 13 % | 4 % | 636 | |
4 | 8 % | 0 % | 95 % | 15.5 | -29% | 16 % | 39 % | 594 | |
5 | 52 % | 0 % | 38 % | 22 % | -28 % | 9 % | 636 | ||
6 | 8 % | 10 % | 23 % | -16 % | -21 % | 68 % | 432 |
Percentage inhibition of NO production at 20 μg/ml.
Percentage inhibition of NFκB at 20 μg/ml.
IC50 value (μM) against NFκB.
Percentage inhibition of aromatase at 20 μg/ml.
IC50 value (μM) against aromatase.
Percentage inhibition of COX-1 at 10 μg/ml.
Percentage inhibition of COX-2 at 10 μg/ml.
Percentage inhibition of QR2 at 11.5 μg/ml.
Molecular weight of compound interacting QR2.