Skip to main content
. 2010 Apr 14;30(15):5357–5367. doi: 10.1523/JNEUROSCI.5017-09.2010

Figure 3.

Figure 3.

Basal and poststress corticolimbic gene expression in C57BL/6J and DBA/2J. A, Basal gene expression differed markedly between C57BL/6J and DBA/2J. Relatively more differences were evident in the hippocampus than the amygdala and vmPFC. There was extensive overlap of differentially expressed genes across the three brain regions. B, C57BL/6J and DBA/2J showed an approximately equal number of gene expression changes after repeated stress in the amygdala and vmPFC, whereas C57BL/6J showed more changes in the hippocampus than DBA/2J. Gene expression changes associated with stress were highly divergent between C57BL/6J and DBA/2J, with very few genes showing alterations in both these strains in any region (n = 3 per strain under stress). C, Significant gene expression differences, and confirmation by RT-PCR (in parentheses), are shown. Symbols indicate upregulation (↑), downregulation (↓), and unconfirmed (−). **p < 0.01; *p < 0.05.