Table1.
| Did NOt Escalate to Full-Syndrome (n = 109) |
Escalated to Full-Syndrome (n = 116) |
Hazards Ratio (95% CI) |
Generalized R2 | |
|---|---|---|---|---|
| Demographic variables | ||||
| Female | 53.7% | 73.0% | 1.80 (1.14–2.84) | 0.0339 |
| Age (SD), y | 16.57 (1.11 ) | 16.58 (1.12) | 0.93 (0.78–1.11) | 0.0028 |
| White | 94.4% | 93.6% | 0.84 (0.43–1.62) | 0.0008 |
| No. of biological parents living at home | 1.56 (0.55) | 1.54 (0.58) | 0.88 (0.6 1–1.27) | 0.0022 |
| Depressive symptomsb | 0.0008 | |||
| Depressed mood | 96.9% | 95.7% | O.81 (0.29–2.27) | |
| Loss of interest or pleasure | 67.5% | 61.3% | 0.83 (0.55–1.26) | 0.0037 |
| Appetite or weight disturbance | 46.3% | 44.0% | 0.92 (0.61–1.3S) | 0.0007 |
| Sleep disturbance | 57.5% | 56.3% | 0.93 (0.62–1.40) | 0.0005 |
| Psychomotor disturbance | 45. 1% | 29.3% | 0.58 (0.38–0.91) | 0.0292 |
| Loss of energy | 48.8% | 54.6% | 1.09 (0.73–1.65) | 0.0009 |
| Worthlessness or guilt | 38.7% | 47.9% | 1.36 (0.91–2.01) | 0.0110 |
| Trouble concentrating/indecisiveness | 63.2% | 59.6% | 0.90 (0.59–1.36) | 0.0011 |
| Thoughts of death or suicide | 14.8% | 24.1% | 1.89 (1.19–3.01) | 0.0299 |
| Depression severity (BDI) (SD) | 6.21 (6.91) | 9.44 (6.58) | 1.05 (1.02–1.07) | 0.0545 |
| Lifetime comorbidity at T1 | ||||
| Anxiety | 4.3% | 14.9% | 2.19 (1.38–3.49) | 0.0295 |
| Disruptive behavior (ODD or conduct) | 4.9% | 2.8% | 0.83 (0.25–2.68) | 0.0049 |
| ADHD | 1.9% | 2.1% | 1.37 (0.44–4.24) | 0.0008 |
| Alcohol use | 4.3% | 4.3% | 1.14 (0.51–2.53) | 0.0003 |
| Drug use | 4.3% | 2.1% | 0.64 (0.20–2.03) | 0.0022 |
| Medical/health symptoms (SD) | 9.10 (5.75) | 13.49 (8.05) | 1.06 (1.04–1.09) | 0.0990 |
| Percent of family members with conditionc | ||||
| Depressive disorders (SD) | 24.6% (26.3%) | 33.6% (31.3%) | 2.70 (1.40–5.22) | 0.0648 |
| Anxiety disorders (SD) | 13.9% {19.4%) | 10.2% (20.2%) | 0.69 (0.21–2.26) | 0.0311 |
| Alcohol use disorders (SD) | 30.0% (28.6%) | 29.8% (30.0%) | 1.15 (0.57–2.37) | 0.0299 |
| Drug use disorders (SD) | 15.2% (22.3%) | 17.8% (25.4%) | 1.77 (0.81–3.88) | 0.0372 |
Note: Statistically significant associations are in bold. ADHD = attention-deficit/hyperactivity disorder; BDI = Beck Depression Inventory; CI = confidence interval; ODD = oppositional defiant disorder.
a
Percentages/hazards ratios/R2 values are weighted by probability of participation in T3.
b
All symptoms are lifetime, except for depression severity, which was assessed at T1.
c
These analyses include three covariates—percentage of family members directly interviewed, percentage of parents (versus Siblings), and percentage of female.