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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Jan 14;30(4):796–801. doi: 10.1161/ATVBAHA.109.199158

Figure 4. Correlation of ABCA1 Efflux to the Concentration of preβ-1 HDL in Serum with Similar High or Low HDL-C.

Figure 4

ABCA1 efflux from cAMP J774 cells was the Probucol sensitive efflux measured after 4h incubation with 2.8% apoB-depleted serum from specimens with similar HDL-C (HDL-C±6%) at either the 25th percentile (open circles: HDL-C=48, range=45-51, n=22) or the 75th percentile (open triangles: HDL-C=73, range 69-77, n=18). The specific contribution of ABCA1 to cholesterol efflux from cAMP treated J774 macrophages was significantly associated to the serum level of preβ-1 HDL (r2=0.425, p=0.0002, n=29) measured by 2D gels. All procedures as in methods.