TABLE 5.
Mood and COMT Polymorphism
| Males (n = 181) | Females (n = 211) | |||||||
|---|---|---|---|---|---|---|---|---|
| Mood score/polymorphism | Base model | Full model | Base model | Full model | ||||
| Beta | Sig. | Beta | Sig. | Beta | Sig. | Beta | Sig. | |
| POMS Mood–Tension Score | ||||||||
| COMT - Het | 1.264 | .157 | .987 | .243 | ||||
| COMT - Mut | 2.264 | .019 | 2.496 | .007 | ||||
| Linear | 1.130 | .019 | 1.250 | .007 | ||||
| POMS Mood–Depression Score | ||||||||
| COMT - Het | .835 | .459 | .596 | .581 | ||||
| COMT - Mut | 2.381 | .053 | 2.452 | .037 | ||||
| Linear | 1.140 | .062 | 1.217 | .040 | ||||
| POMS Mood–Fatigue Score | ||||||||
| COMT - Het | 1.987 | .025 | 1.856 | .027 | ||||
| COMT - Mut | 1.661 | .083 | 2.279 | .014 | ||||
| Linear | 0.843 | .078 | 1.140 | .013 | ||||
| POMS Mood–Confusion Score | ||||||||
| COMT - Het | .755 | .187 | .706 | .201 | ||||
| COMT - Mut | 1.336 | .032 | 1.392 | .021 | ||||
| Linear | 0.655 | .034 | 0.694 | .021 | ||||
| POMS Mood–Overall Score | ||||||||
| COMT - Het | 7.019 | .097 | 6.579 | .097 | ||||
| COMT - Mut | 10.344 | .025 | 12.565 | .004 | ||||
| Linear | 5.210 | .022 | 6.046 | .005 | ||||
Note. Only gender-specific categories with significant associations are shown; beta values represent the strength of the association between 0 and 100%. Boldfaced numerals indicate significant (p < .05); italicized numerals indicate not significant (p > .05; values are shown for comparison between base and full models).