Table 3.
Charlson Comorbidity Index and Charlson Comorbidity Index components
| COPD patients (N = 59,906) | Control patients (N = 117,546) | P value | |
|---|---|---|---|
| Charlson Comorbidity Index, mean (SD) | |||
| 2.85 (1.46) | 1.84 (1.52) | <0.0001 | |
| Charlson comorbidity index components, n (%) | |||
| Myocardial infarction | 1828 (3.05) | 3103 (2.64) | <0.0001 |
| Congestive heart failure | 6270 (10.47) | 5937 (5.05) | <0.0001 |
| Peripheral vascular disease | 3238 (5.41) | 4238 (3.61) | <0.0001 |
| Cerebrovascular disease | 3848 (6.42) | 7701 (6.55) | 0.3010 |
| Dementia | 681 (1.14) | 1965 (1.67) | <0.0001 |
| Chronic pulmonary disease | 59,906 (100) | 0 (0) | na |
| Rheumatologic disease | 992 (1.66) | 1473 (1.25) | <0.0001 |
| Peptic ulcer disease | 2083 (3.48) | 2586 (2.20) | <0.0001 |
| Mild liver disease | 518 (0.86) | 981 (0.83) | 0.5121 |
| Diabetes – mild to moderate | 8182 (13.66) | 21,613 (18.39) | <0.0001 |
| Diabetes with chronic complications | 2257 (3.77) | 5573 (4.74) | <0.0001 |
| Paraplegia or hemiplegia | 418 (0.70) | 1074 (0.91) | <0.0001 |
| Renal disease | 1425 (2.38) | 2672 (2.27) | 0.1614 |
| Any malignancy/lymphoma/leukemia | 6367 (10.63) | 11,561 (9.84) | <0.0001 |
| Moderate or severe liver disease | 143 (0.24) | 386 (0.33) | 0.0011 |
| Metastatic solid tumor | 0 (0) | 0 (0) | na |
| Acquired immune deficiency syndrome (AIDS) | 510 (0.85) | 1473 (1.25) | <0.0001 |
Abbreviations: COPD, chronic obstructive pulmonary disease; SD, standard deviation.