Table 3.

Binding of non-selective CB receptor ligand, [³H]CP55540, in pluteus, spleen or brain, ± CB2 or CB1 receptor antagonist

Tissue	Total [3H] CP55540 bound fmol/μg (mean ± SEM)	+ CB2 receptor antagonist, SR144	Total [3H]CP55540 bound	+ CB1 receptor antagonist, SR141
Pluteus	0.009 ± 0.002	0.002 ± 0.002	0.007 ± 0.002	0.007 ± 0.005
Brain	0.099 ± 0.039	0.049 ± 0.022	0.160 ± 0.01	0.048 ± 0.012∗
Spleen	0.046 ± 0.002	0.006 ± 0.006∗	ND	ND

Experiments were run in duplicate with two replicates for each condition.

^∗p < 0.05 (one-way ANOVA; Newman-Keuls post-hoc test). ND = Not determined.