. Author manuscript; available in PMC: 2010 May 10.

Published in final edited form as: Am J Gastroenterol. 2009 Jun 9;104(8):2047–2056. doi: 10.1038/ajg.2009.281

Table 4. Effect of BMI on mortality among colorectal cancer patients in strata of STMN1 status.

	Colorectal cancer–specific mortality			Overall mortality
	No. of deaths/cases	Stage-matched HR (95% CI)	Multivariate HR (95% CI)	No. of deaths/cases	Stage-matched HR (95% CI)	Multivariate HR (95% CI)
STMN1 (−)
BMI <30 kg/m²	56/199	1 (referent)	1 (referent)	89/199	1 (referent)	1 (referent)
BMI ≥30 kg/m²	12/39	0.95 (0.50–1.80)	0.51 (0.24–1.07)	18/39	0.95 (0.56–1.61)	0.71 (0.40–1.28)
STMN1 (+)
BMI <30 kg/m²	55/237	1 (referent)	1 (referent)	95/237	1 (referent)	1 (referent)
BMI ≥30 kg/m²	13/45	2.21 (1.18–4.15)	2.36 (1.18–4.69)	20/45	1.67 (1.01–2.75)	1.93 (1.13–3.32)

BMI, body mass index; CI, confi dence interval; HR, hazard ratio.

The multivariate Cox model included the BMI variable stratifi ed by STMN1 category, age, year of diagnosis, sex, family history of colorectal cancer, tumor location, stage, grade, KRAS, BRAF, PIK3CA, p53, p21, p27, cyclin D1, β-catenin, COX-2, FASN, LINE-1 methylation, microsatellite instability (MSI), CpG island methylator phenotype (CIMP), and STMN1. SAS codes to stratify the BMI variable by STMN1 category are available upon request.