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. 2009 Dec 22;118(5):627–634. doi: 10.1289/ehp.0901510

Figure 1.

Figure 1

Arsenic inhibits neurite outgrowth in N2a cells. Cells were induced to differentiate for 48 hr in media containing RA or RA plus 0.5–5 μM As (A) or for 0–48 hr in growth medium alone without treatment (control), RA, or RA plus 3 μM As (B). Images are typical fields of cells viewed with an inverted light microscope; bars = 100 μm. (C) Percentage of cells exhibiting neurites (left) and the average length of neurites (right) in 200 cells treated as in A (top) and as in B (bottom). Each data point is the mean ± SE of three independent experiments.

*p <0.05 compared with RA treatment alone.