Table 1. Effect of mutation of STIM1(⁶⁸⁴KK⁶⁸⁵) and of TRPC1(⁶³⁹DD⁶⁴⁰) on TRPC1 channel activity.

HEK cells were transfected with the TRPC1 mutants alone (first column) or with the indicated STIM1 mutants. The results are the mean±s.e.m. (n≥4 for each condition) of the current in pA recorded at −100 mV and extracted from the −100 to +100 RAMPs. Highlighted in red are full rescues and in blue partial rescues. ND=not determined. (reproduced from [18]).

^*P<0.05 relative to wild-type TRPC1+STIM1

ND = Not determined