Fig. 8.

Foxd3 knockdown in sym1 embryos enhances penetrance of mesodermal defects. Cross progeny of wild-type (WT) or sym1 heterozygous (Sym1) adults were injected at the one-cell stage with a mixture of foxd3MO1 and foxd3MO2 (MO) (total dosage 2.5ng) and craniofacial and axial phenotypes were assessed at 5dpf. Quantification of the three phenotypic classes is shown as a percentage of total: Wild-type (wt, black), craniofacial defect (reduced jaw, gray), craniofacial defects together with axial defects (short, white).