Fig. 3. Statin postconditioning effect in primary cultures.
Primary cultures of bovine pulmonary arterial endothelial cells were exposed to or not exposed to a 5-h oxygen-glucose deprivation (OGD) and 1-h simulated reperfusion. The cells were posttreated with or without 1 or 2 µM simvastatin or 2 or 4 µM atorvastatin for 1 h immediately after the OGD. Results are means ± S.D. (n = 18 to 54 for panel A and 18 to 54 for panel B). * P < 0.05 compared with control. ^ P < 0.05 compared with OGD only.