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. Author manuscript; available in PMC: 2011 Jun 25.
Published in final edited form as: Eur J Pharmacol. 2010 Mar 31;636(1-3):114–120. doi: 10.1016/j.ejphar.2010.03.028

Fig. 5. Inhibition of superoxide production after oxygen-glucose deprivation (OGD) and simulated reperfusion by statin post-treatment.

Fig. 5

Bovine pulmonary arterial endothelial cells were exposed to or not exposed to a 5-h OGD and 1-h simulated reperfusion. The cells were posttreated with or without 2 µM simvastatin or 4 µM atorvastatin in the presence or absence of 20 µM GGPP for 1 h immediately after the OGD. Results are means ± S.D. (n = 18 – 34). * P < 0.05 compared with control. ^ P < 0.05 compared with OGD only. # P < 0.05 compared with OGD + simvastatin post-treatment. & P < 0.05 compared with OGD + atorvastatin post-treatment.