Skip to main content
. Author manuscript; available in PMC: 2011 Jun 25.
Published in final edited form as: Eur J Pharmacol. 2010 Apr 2;636(1-3):65–72. doi: 10.1016/j.ejphar.2010.03.033

Fig.1.

Fig.1

Effects of a single dose of morphine on PGi neuronal activities. (A–D) Histograms of excitatory and inhibitory effects of a single dose of morphine on PGi neurons. Morphine was injected i.c.v. at time 0. Naltrexone or saline vehicle was injected 20 min after morphine injection. (E and F) Summary of the reversal effects of naltrexone on acute morphine-induced inhibition and excitation of PGi neurons (E. i.c.v. injection, F. i.v. injection). Bars represent mean firing rate of PGi neurons 10 min before morphine injection (baseline), 10–20 min after morphine injection and 0–10 min after naltraxone injection, respectively. Error bars represent S.E.M. ***P< 0.001, **P<0.005, *P<0.05 (One-way repeated measures analysis of variance and Boferonii test).

HHS Vulnerability Disclosure