Table 3.
Sequences whose expression was decreased by temperature, independent of clinical diagnosis
| Common name(s) | Affymetrix ID | ANCOVA temperature P | Correlation coefficient | Correlation P | Note |
|---|---|---|---|---|---|
| Cell adhesion | |||||
| CD47 antigen (CD47) (Rh-related antigen, integrin-associated signal transducer) | 242974_at | 0.005 | −0.166 | 0.002 | |
| Cell growth, proliferation, and differentiation | |||||
| MAL; mal, T-cell differentiation protein | 204777_s_at | 0.045 | −0.143 | 0.007 | (2) |
| HSPs, chaperonins, and co-chaperonins | |||||
| DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3) | 205963_s_at | 0.009 | −0.185 | <0.001 | |
| Heat shock 70 kD protein 8 (HSPA8); HSC-70 | 221891_x_at | 0.001 | −0.182 | 0.001 | (1, 4) |
| 208687_x_at | 0.006 | −0.178 | 0.001 | ||
| 210338_s_at | 0.018 | −0.144 | 0.007 | ||
| Heat shock 70 kDa protein 9B (HSPA9B) (mortalin 2); 75 kDa glucose-regulated protein (GRP75) | 200690_at | 0.019 | −0.141 | 0.008 | (2) |
| HSP 70-interacting protein (HSPBP1); HSP 70 binding protein | 202415_s_at | 0.033 | −0.159 | 0.003 | |
| Spastic ataxia of Charlevoix–Saguenay (sacsin) (SAC) | 213262_at | 0.038 | −0.124 | 0.020 | (1) |
| TNF receptor-associated protein 1 (TRAP1); HSP75; HSP90L | 201391_at | 0.016 | −0.187 | <0.001 | (2) |
| Immune function | |||||
| Sterile alpha and TIR motif containing 1 (SARM1); KIAA0524 | 213257_at | 0.021 | −0.154 | 0.004 | (3) |
| Toll-like receptor 6 (TLR-6) | 207446_at | 0.029 | −0.122 | 0.022 | |
| Toll-like receptor 7 (TLR-7) | 220146_at | 0.003 | −0.209 | <0.001 | |
| Signal transduction | |||||
| Ring finger protein 216 (RNF216); TRIAD3 | 218425_at | 0.039 | −0.122 | 0.022 | |
| Translation | |||||
| Ribosomal protein L13a (RPL13A); 23 kD highly basic protein, 60S ribosomal protein L13a | 212790_x_at | 0.020 | −0.172 | 0.001 | |
| 210646_x_at | 0.026 | −0.168 | 0.002 | ||
| Ribosomal protein L37a (RPL37A) | 201429_s_at | 0.011 | −0.192 | <0.001 | |
| Ribosomal protein S2 (RPS2) | 203107_x_at | <0.001 | −0.267 | <0.001 | |
| 221798_x_at | <0.001 | −0.261 | <0.001 | ||
| Ribosomal protein S23 (RPS23) | 200926_at | 0.034 | −0.150 | 0.005 | (1) |
| Ribosomal protein S3 (RPS3) | 208692_at | 0.013 | −0.173 | 0.001 | |
(1) Correlation coefficient and correlation P computed by Spearman’s rho; (2) previously reported to show decreased expression after exertional heat injury (Sonna et al. 2004); (3) also decreased after exertional heat injury (Sonna et al. 2004; previously unpublished finding); (4) previously reported to show increased expression after exertional heat injury (Sonna et al. 2004)