Table 4.
Affymetrix ID | Common name(s) | ANCOVA P value for: | Note | ||
---|---|---|---|---|---|
Diagnosis (noninfectious SIRS vs. sepsis) | Diagnosis × temperature | Temperature | |||
205242_at | Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) (CXCL13) | 0.026 | 0.025 | 0.535* | |
202865_at | DnaJ (Hsp40) homolog, subfamily B, member 12 (DNAJB12) | 0.051* | 0.050 | 0.502* | |
206782_s_at | DnaJ (Hsp40) homolog, subfamily C, member 4 (DNAJC4) | 0.019 | 0.019 | 0.007 | |
223000_s_at | F11 receptor (F11R) | 0.046 | 0.044 | 0.527* | |
215363_x_at | Folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1) | 0.050 | 0.048 | 0.875* | |
211220_s_at | Heat shock transcription factor 2 (HSF-2) | 0.037 | 0.036 | 0.589* | |
200799_at | Heat shock 70 kD protein 1A (HSPA1A); HSP 70-1A | 0.030 | 0.035 | 0.106* | (3,4) |
202581_at | Heat shock 70 kDa protein 1B (HSPA1B); HSP 70-1B | 0.025 | 0.027 | 0.285* | (3,4) |
210189_at | Heat shock 70 kDa protein 1-like (HSPA1L) | 0.042 | 0.047 | 0.442* | |
202859_x_at | Interleukin 8 (IL-8); CXC chemokine ligand 8 | 0.003 | 0.003 | 0.045 | (2) |
214461_at | Lipopolysaccharide binding protein (LBP) | 0.029 | 0.028 | 0.998* | (1) |
210367_s_at | Prostaglandin E synthase (PTGES) | 0.034 | 0.036 | 0.320* |
(1) Serum LBP protein has been reported to be differentially expressed in SIRS vs. sepsis (Prucha et al. 2003); (2) serum IL-8 has been reported to be differentially expressed in SIRS vs. severe sepsis/septic shock (Rodriguez-Gaspar et al. 2001); (3) HSP 70 protein has been reported to be differentially expressed in SIRS vs. sepsis (Adib-Conquy and Cavaillon 2007); (4) HSP 70A1A and A1B mRNA have been reported to show increased expression after exercise (Connolly et al. 2004) and exertional heat injury (Sonna et al. 2004)
*P > 0.05, not statistically significant