Table 5.

Expression patterns produced by the interaction of temperature and clinical diagnosis

Expression pattern	Gene	Sepsis, N = 175					Noninfectious SIRS, N = 177					Note
(See text)		P	R	R2	Significant?	Temperature effect	P	R	R2	Significant?	Temperature effect
1	DNAJC4	<0.001	0.280	0.078	Yes	Up	0.801	0.019	<0.001	No	No effect
2	HSF-2	0.211	−0.095	0.009	No	No effect	0.092	0.127	0.016	Trendb	Up
	HSP70-1A	0.673	−0.032	0.001	No	No effect	0.024	0.169	0.029	Yes	Up
	HSP70-1B	0.387	−0.066	0.004	No	No effect	0.025	0.168	0.028	Yes	Up
	HSPA1L	0.351	−0.071	0.005	No	No effect	0.063	0.140	0.020	Trendb	Up
	PTGES	0.402	−0.064	0.004	No	No effect	0.037	0.157	0.025	Yes	Up
3	CXCL13	0.083	−0.131	0.017	Trendb	Down	0.598	0.040	0.002	No	No effect	a
	F11R	0.035	−0.159	0.025	Yes	Down	0.376	0.067	0.004	No	No effect
	FOLH1	0.112	−0.120	0.014	Trendb	Down	0.204	0.096	0.009	No	No effect
	LBP	0.074	−0.135	0.018	Trendb	Down	0.165	0.105	0.011	No	No effect
4	DNAJB12	0.300	0.079	0.006	No	No effect	0.093	−0.127	0.016	Trendb	Down
	IL-8	0.840	−0.015	<0.001	No	No effect	0.001	−0.248	0.062	Yes	Down	a

P and R values were computed by Pearson’s correlation unless otherwise specified

^aP and R values calculated by Spearman’s rho

^bA trend was defined as 0.05 < P < 0.125