Fig. 7.

LPS induced differentiation does not induce an arrest in protein synthesis. I.29 μ⁺ B cells were treated with LPS (a) or conventional UPR inducers (b) for the indicated times and then pulse-labeled with [³⁵S] methionine and cysteine for 5 min. Cell lysates were analyzed directly by SDS-PAGE and proteins were visualized by autoradiography. c An aliquot of cell lysates from the indicated times after LPS induction were examined by Western blotting for Ig heavy and light chain expression